Brain Folding Slackens With Age: A New Discovery Revealed

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Honor Whiteman from Medicalnewstoday.com says that the crevices and ridges make the organ distinct. A theory says that the folding is linked to evolution. It is a means to condense the cortex and enhance functions. Researchers have discovered how folds occur and its relation to aging.

The scientists found that it loses tension when people get older. Apparently, it is even more obvious for patients with Alzheimer’s. This is critical as it is responsible for functions like consciousness, language, intelligence and memory.

Brain Folding ‘Slackens’ With Age, Study Finds

Theory holds that the folding brain is a result of evolution, a way to condense the cerebral cortex and improve brain cell communication and functioning. Now, researchers have shed light on how folding occurs in the human brain and how it changes with age. Read more…

Sciencefocus.com writer Gertie Goddard says that the lack of tension or elasticity is part of the “universal law.” This leads us to those who stand out – especially the ones who already have neurodegenerative diseases like Alzheimer’s. This can possibly help out diagnosis as well as the treatment of the condition.

Lead author Dr. Yujiang Wang says that they saw a parameter that goes down with age. They interpreted it as the change in the elasticity. This study has a good potential for future use because factors like age, gender and disease can be compared.

Brains ‘Slacken’ As They Age

It is amazing to think that if just one half of the cerebral cortex – the wrinkled outer layer of neural brain tissue – was unfolded and laid flat, it would have a surface area one and half times the size of an A4 paper (or 100,000mm-squared to be precise). Read more…

D.C. Demetre from Reliawire.com reports that in female subjects, the brains are less slightly folded compared with the male brains. Their ages are the same. Dr. Wang says that for the first time, they have a method of quantifying the folding occurrences in humans.

The author says the study needs more work and investigation but it’s has promising leads in Alzheimer’s. The ones affected by this condition have similar folding which is the same with premature aging of the cortex.

How Brain Cortical Folding Changes As You Age

Throughout the lifespan of healthy individuals, cortical folding changes in the same way in both men and women but in those with Alzheimer’s disease the change in the brain folding was significantly different. Read more…

The study is still fairly new and there might be advances in the next few years. Future investigations may provide the way for new discoveries about the brain.

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