Wednesday, June 1, 2016

Fungicides May Damage Children’s Teeth Quickly

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Recent studies show that two common chemicals used in everyday living like bisphenol A (BPA) a common substance used in making food packages and fungicides may damage children’s teeth that could be irreversible.

BPA and fungicides may damage children’s teeth

In a study published by the French National Institute of Health and Medical Research, lead study author Dr. Katia Jedeon, found that exposure to BPA and fungicides by children at an early age may develop a condition where it interferes with the production of hormones that are essential for dental health.

Their findings were published in 2016 held recently in Munich, Germany, where BPA and certain fungicide have been proven to be hormone disuptors, which means they interfere in hormone functioning and increases the risk of hormones functioning improperly.

BPA is commonly used in the production of resins and plastics often used for food and drink packages, on the other hand, vinclozolin is a leading fungicide formula used to protect orchards, vineyards and golf courses.

Dr. Jedeon claimed that enamel deficiency among children may play a direct role in a condition  known as the molar incisor hypomineralization (MIH) and has been found to affect as much as 18 percent.

It is the developmental condition that is highlighted by enamel defects that occur in the child’s first permanent teeth, commonly the incisors and molars. These defects have been found to be irreversible because once the tooth enamel is damaged it could no longer grow back.

Symptoms of MIH are heightened tooth sensitivity, specifically when eating cold food and drinks, with a high risk of developing dental caries. The teeth appears yellow, brown or creamy coloured and could chip away easily with slight pressure applied to it.

During the study, Dr. Jedeon and her team exposed laboratory rats to daily doses of BPA and vinclozolin from birth up until the first 30 days, with doses of the chemicals that were equal to the average dose a human would be generally exposed to.

On the last day of the exposure, they collected cells from the rat’s teeth surface and found that the expression of two genes KLK4 and SLC5A8 were altered. These hormones are responsible in regulating the mineralization of tooth enamel.

They also discovered that the sex hormones estrogen and testosterone were also found to increase the expression of these two genes that produce tooth enamel.

Dr. Jedeon stresses that these studies could help science come up with measures to develop better alternatives for packaging materials and fungicides that may damage children’s teeth and reduce the effects of these conditions to one’s health and lifestyle.

Image Credit: Chemicals in food packaging, fungicides might damage children’s teeth – MNT 

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